Chlamydia pneumoniae Infection of Vascular Smooth Muscle and Endothelial Cells Activates NF-kB and Induces Tissue Factor and PAI-1 Expression A Potential Link to Accelerated Arteriosclerosis
نویسنده
چکیده
Accelerated Arteriosclerosis B and Induces Tissue Factor and PAI-1 Expression : A Potential Link to κ Activates NFInfection of Vascular Smooth Muscle and Endothelial Cells Chlamydia pneumoniae Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 1999 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/01.CIR.100.13.1369 1999;100:1369-1373 Circulation. http://circ.ahajournals.org/content/100/13/1369 World Wide Web at: The online version of this article, along with updated information and services, is located on the
منابع مشابه
Chlamydia pneumoniae infection of vascular smooth muscle and endothelial cells activates NF-kappaB and induces tissue factor and PAI-1 expression: a potential link to accelerated arteriosclerosis.
BACKGROUND Recent reports link C. pneumoniae infection of arteriosclerotic lesions to the precipitation of acute coronary syndromes, which also feature tissue factor and plasminogen activator inhibitor 1 (PAI-1) overexpression. We investigated whether or not C. pneumoniae can induce thrombogenicity by upregulation of procoagulant proteins. METHODS AND RESULTS Human vascular endothelial and sm...
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Objective—Chlamydia pneumoniae has been associated with atherosclerosis. Infection of vascular endothelial cells with C pneumoniae increases the expression of proatherogenic cytokines mediated by nuclear factor (NF)-kB, a transcription factor. The present study was designed to test the effect of aspirin on C pneumoniae–induced NF-kB activation, interleukin expression, and bacterial development ...
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OBJECTIVE Chlamydia pneumoniae has been associated with atherosclerosis. Infection of vascular endothelial cells with C pneumoniae increases the expression of proatherogenic cytokines mediated by nuclear factor (NF)-kappaB, a transcription factor. The present study was designed to test the effect of aspirin on C pneumoniae-induced NF-kappaB activation, interleukin expression, and bacterial deve...
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